High Volume
By Charlie on Mar 2, 2008 in Hearing & Orthepedic

Why does diabeties result in high volume of urine output?
Why does diabeties result in high volume of urine output?
I understand that with diabetes, the proximal tube/loop of henle/etc cannot get rid of all the excess glucose that is pumped through the nephrons, resulting in sugary urine. BUT, I don’t understand how the presence of glucose would increase the VOLUME of urine. Can someone explain?
It has to do with osmosis. If you have diabetes then that means your body is not breaking down and using glucose properly, it sort of floats around in your blood causing your blood to become hypertonic(this means there is more solute or glucose in the blood vs surrounding areas) so the glucose will move from a high concentration to a lower concentration in other words glucose will move into your bladder and since water also moves from high to lower concentration your bladder will pull more water in causing you to pee more. In other words now that your bladder contains higher levels of glucose it is hypertonic and osmosis will take place moving the higher concentration of water outside your bladder to a lower concentration inside your bladder causing you to run to the bathroom. Think of it as if you are in a house with a Bunch of people and it got to be too many you would diffuse outside so hence you are moving from higher to lower concentration just like water does when glucose when glucose crowds your bladder!! Hope that this was somewhat helpfull!!???
Good luck!!
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